HCG

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone composed of an alpha and beta subunit. In research settings, it is studied for its activity at the LH/CG receptor and its role in gonadal steroidogenesis, reproductive endocrinology, and cell signaling assays.

HCG (Human Chorionic Gonadotropin) is a glycoprotein hormone that activates the LH/CG receptor. It is used in laboratory research as a tool for studying gonadal steroidogenesis, reproductive signaling, and gonadotropin receptor biology. Supplied as a lyophilized research reagent.

HCG was first identified in the 1920s from the urine of pregnant women. Its characterization as a heterodimeric glycoprotein with LH receptor agonist activity established it as a foundational tool in reproductive biology research. Recombinant and urinary-derived preparations have been used extensively in preclinical endocrinology studies.

Published research demonstrates that HCG binds to the LH/CG receptor with high affinity, activating cAMP-dependent steroidogenic pathways. In vitro studies utilize HCG to stimulate Leydig cell testosterone production and granulosa cell progesterone synthesis. It remains a standard reference compound in reproductive endocrinology and gonadotropin receptor signaling research.